Phytochemical Screening and Larvicidal Activity of Kebiul (Caesalpinia Bonduc. L) Seed Kernel Against Aedes Aegypti Mosquito

Popi Rantina; Dwi Fitri Yani; Suci Permata Sari; Dany Raihan

doi:10.21580/wjc.v5i1.9476

Phytochemical Screening and Larvicidal Activity of Kebiul (Caesalpinia Bonduc. L) Seed Kernel Against Aedes Aegypti Mosquito

- Universitas Islam Negeri Raden Fatah Palembang, Indonesia

* - Universitas Islam Negeri Raden Fatah Palembang, Indonesia

- Universitas Islam Negeri Raden Fatah Palembang, Indonesia

- The University of British Columbia, Vancouver, Canada

(*) Corresponding Author

DOI: 10.21580/wjc.v5i1.9476

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Dengue Hemorrhagic Fever (DHF) is caused by an infected A. aegypti mosquito, which can cause serious bleeding, a sudden drop in blood pressure and even death. Kebiul seed kernel extract is thought to contain flavonoid compounds, terpenoids, saponins and steroids that can be used as larvicides. The purpose of this study was to determine the toxicity of the extract, n-hexane fraction, and ethanol fraction of kernel seed (C. bonduc. L) against A. aegypti mosquito larvae. This study used the methods of extraction, phytochemical screening, and toxicity tests by calculating larval mortality. Based on the results of phytochemical screening, extract of kernel seed (C. bonduc. L) contains tannins, flavonoids, alkaloids, steroidal saponins and terpenoids. Toxicity test (LC₅₀values) of extract, n-hexane fraction, and ethanol fraction of kernel seed (C. bonduc. L) are 368,566 g/mL, 483,010 g/mL, 338,361 g/mL. The LC₅₀ value < 1000 ppm has a toxic effect, so the kernel seed has the potential to be used as a larvicide.

Keywords: Aedes aegypti; Caesalpinia bonduc. L; Dengue hemorrhagic fever

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