This study explores the invocation of Barakah, a significant aspect of Yoruba Muslim spirituality in Nigeria, and its role as a potent force of well-being. Barakah is a concept deeply rooted in Yoruba Muslim culture, symbolizing divine blessings and spiritual abundance. This study aims to investigate how the invocation of Barakah contributes to the holistic well-being of Yoruba Muslims in Nigeria. Drawing upon qualitative research methods, including interviews, observations, and textual analysis, this study offers an in-depth understanding of the spiritual practices and beliefs associated with the invocation of Barakah. It explores the reasons behind its significance and the impact it has on individuals’ well-being, encompassing physical, mental, and emotional dimensions. The study explores how Yoruba Muslims invoke Barakah through specific rituals such as prayer, recitation of the Qur’an, supplication, seeking intercession of saints and acts of charity. Furthermore, it delves into the belief that Barakah manifests in various aspects of life, including personal relationships, health, finances, and overall success. The findings of this study reveal that the invocation of Barakah acts as a dynamic force in Yoruba Muslim communities, providing spiritual solace, guidance, and a sense of purpose. It emerges as a tool for navigating life’s challenges, fostering resilience, and cultivating gratitude. Moreover, the study brings into fore some anomalies and abuses associated with this practice of invoking Barakah and its implications in the Sharīʽah.