Modifikasi Makanan Enteral Tinggi Asam Amino Essensial

Natalia Desy Putriningtyas*    -  Universitas Negeri Semarang, Indonesia
Listiyani Eka Tyastuti  -  Instalasi Gizi, RSUP Dr. Kariadi Semarang, Indonesia
Sri Purwaningsih  -  Instalasi Gizi, RSUP Dr. Kariadi Semarang, Indonesia

(*) Corresponding Author

This study aims to produce enteral formulations with good taste, proper texture, osmolality, and nutritional value suitable for cancer patients. This study used an experimental design. The preparation of enteral formula was carried out at the Nutrition Laboratory of the Department of Public Health Sciences, Universitas Negeri Semarang, followed by proximate testing at the Food Technology Laboratory of Soegijapranata Catholic University. The sensory test was conducted at a hospital nutrition installation in Semarang city. The panelists in this study were a group of trained panelists totaling 24 nutritionists in the hospital. Statistical analysis uses descriptive analysis by describing organoleptic test data based on the percentage of hedonic level. The results showed that 18 people (75%) liked the color of the product; 13 people (54.2%) liked the taste; 21 people (87.5%) liked the aroma; and the texture of the enteral formula produced was liked by 16 people (66.7%). The resulting enteral formula has an energy content of 1199.8 kcal; protein 161.2 grams; fat 4.8 grams; carbohydrates 107.8 grams; branch chain amino acid (BCAA) 36.8 grams per 1000 ml.

 

Penelitian ini bertujuan untuk menghasilkan formulasi makanan enteral dengan rasa enak, tekstur tepat, osmolalitas dan nilai gizi sesuai bagi penderita kanker. Penelitian ini menggunakan desain eksperimental. Pembuatan formula enteral dilaksanakan di Laboratorium Gizi Jurusan Ilmu Kesehatan Masyarakat Universitas Negeri Semarang. Uji proksimat dilaksanakan di Laboratorium Teknologi Pangan Universitas Katholik Soegijapranata. Uji sensori dilakukan di instalasi gizi rumah sakit wilayah kota Semarang. Panelis pada penelitian ini adalah kelompok panelis terlatih sejumlah 24 ahli gizi di rumah sakit. Analisis statistik menggunakan analisis deskriptif dengan memaparkan data uji organoleptik berdasarkan persentase tingkat hedonik. Hasil penelitian menunjukkan bahwa sebanyak 18 orang (75%) menyukai warna produk yang dihasilkan, 13 orang (54,2%) menyukai rasa, 21 orang (87,5%) menyukai aroma dan tekstur formula enteral yang dihasilkan disukai oleh 16 orang (66,7%). Formula enteral yang dihasilkan memiliki kandungan energi 1199,8 kkal, protein 161,2 gram, lemak 4,8 gram, karbohidrat 107,8 gram, asam amino rantai cabang (BCAA) 36,8 gram setiap 1000 ml.

Keywords: amino acid; enteral formula; ginger; skim milk; isolate protein; asam amino; formula enteral; jahe; susu skim; isolat protein

  1. [BSN] Badan Standar Nasional. (2009), “SNI 3751:2009 Tepung Terigu Sebagai Bahan Makanan”, Badan Standardisasi Nasional, pp. 1–48.
  2. Amano, K., Maeda, I., Ishiki, H., Miura, T., Hatano, Y., Tsukuura, H., Taniyama, T., et al. (2021), “Effects of enteral nutrition and parenteral nutrition on survival in patients with advanced cancer cachexia: Analysis of a multicenter prospective cohort study”, Clinical Nutrition, 40 (3), pp. 1168–1175.
  3. Bernfeld, E., Foster, D.A. (2019), “Glutamine as an Essential Amino Acid for KRas-Driven Cancer Cells”, Trends in Endocrinology and Metabolism, Elsevier Ltd, 30 (6), pp. 357–368.
  4. Bhargava, R., Chasen, M., Elten, M., MacDonald, N. (2020), “The effect of ginger (Zingiber officinale Roscoe) in patients with advanced cancer”, Supportive Care in Cancer, 28 (7), pp. 3279–3286.
  5. Borges, D.O., Freitas, K.A.B. da S., Minicucci, E.M., Popim, R.C. (2020), “Benefits of ginger in the control of chemotherapy-induced nausea and vomiting”, Revista Brasileira de Enfermagem, 73 (2), p. e20180903.
  6. Bumrungpert, A., Pavadhgul, P., Nunthanawanich, P., Sirikanchanarod, A., Adulbhan, A. (2018), “Whey protein supplementation improves nutritional status, glutathione levels, and immune function in cancer patients: a randomized, double-blind controlled trial”, Journal of Medicinal Food, 21 (6), pp. 612–616.
  7. Cederholm, T., Barazzoni, R., Austin, P., Ballmer, P., Biolo, G., Bischoff, S.C., Compher, C., et al. (2017), “ESPEN guidelines on definitions and terminology of clinical nutrition”, Clinical Nutrition, 36 (1), pp. 49–64.
  8. Chow, R., Bruera, E., Chiu, L., Chow, S., Chiu, N., Lam, H., McDonald, R., et al. (2016), “Enteral and parenteral nutrition in cancer patients: A systematic review and meta-analysis”, Annals of Palliative Medicine, 5 (1), pp. 30–41.
  9. Dillon, E.L., Basra, G., Horstman, A.M., Casperson, S.L., Randolph, K.M., Durham, W.J., Urban, R.J., et al. (2012), “Cancer cachexia and anabolic interventions: A case report”, Journal of Cachexia, Sarcopenia and Muscle, 3 (4), pp. 253–263.
  10. Hou, Y., Wu, G. (2018), “Nutritionally essential amino acids”, Advances in Nutrition, 9 (6), pp. 849–851.
  11. Hull, M.A. (2021), “Conference on diet and digestive disease symposium 4: Gi cancers, the role of nutrition in prevention, pathology and management: Nutritional prevention of colorectal cancer”, Proceedings of the Nutrition Society, 80 (1), pp. 59–64.
  12. Jeesan, S.A., Seo, H.S. (2020), “Color-induced aroma illusion: Color cues can modulate consumer perception, acceptance, and emotional responses toward cooked rice”, Foods, 9 (12), pp. 1–19.
  13. Kanda, A., Nakayama, K., Sanbongi, C., Nagata, M., Ikegami, S. and Itoh, H. (2016), “Effects of whey, caseinate, or milk protein ingestion on muscle protein synthesis after exercise”, Nutrients, 8 (6).
  14. Kemenkes Republik Indonesia. (2019), Peraturan Menteri Kesehatan Republik Indonesia Nomor 28 Tahun 2019 Tentang Angka Kecukupan Gizi Yang Dianjurkan Untuk Masyarakat Indonesia, Jakarta.
  15. Lee, D.U., Fan, G.H., Hastie, D.J., Addonizio, E.A., Han, J., Prakasam, V.N., Karagozian, R. (2021), “The clinical impact of malnutrition on the postoperative outcomes of patients undergoing gastrectomy for gastric cancer: Propensity score matched analysis of 2011–2017 hospital database”, Clinical Nutrition ESPEN, 46 (February), pp. 484–490.
  16. Nie, C., He, T., Zhang, W., Zhang, G., Ma, X. (2018), “Branched chain amino acids: Beyond nutrition metabolism”, International Journal of Molecular Sciences, 19 (4), pp. 1–16.
  17. Pelly, F.E., Tweedie, J. (2021), “Inclusion of nutrition expertise in catering operations at a major global sporting event: a qualitative case study using a foodservice systems approach”, Journal of the Academy of Nutrition and Dietetics, 121 (1), pp. 121–133.
  18. Prado, C.M., Purcell, S.A., Laviano, A. (2020), “Nutrition interventions to treat low muscle mass in cancer”, Journal of Cachexia, Sarcopenia and Muscle, 11 (2), pp. 366–380.
  19. Rolland, Y., Van Kan, G.A., Gillette-Guyonnet, S., Vellas, B. (2011), “Cachexia versus sarcopenia”, Current Opinion in Clinical Nutrition and Metabolic Care, 14 (1), pp. 15–21.
  20. Rondanelli, M., Klersy, C., Terracol, G., Talluri, J., Maugeri, R., Guido, D., Faliva, M.A., et al. (2016), “Whey protein, amino acids, and Vitamin D supplementation with physical activity increases fat-free mass and strength, functionality, and quality of life and decreases inflammation in sarcopenic elderly”, American Journal of Clinical Nutrition, 103 (3), pp. 830–840.
  21. Sung, H., Ferlay, J., Siegel, R.L., Laversanne, M., Soerjomataram, I., Jemal, A., Bray, F. (2021), “Global Cancer Statistics 2020: GLOBOCAN Estimates of incidence and mortality worldwide for 36 cancers in 185 countries”, CA: A Cancer Journal for Clinicians, 71 (3), pp. 209–249.
  22. The Global Cancer Observatory. (2020), “Cancer Incident in Indonesia”, International Agency for Research on Cancer, 858, pp. 1–2.
  23. Zaki, I., Ayu, W., Putri, K. (2021), “Kualitas organoleptik , kandungan gizi , dan densitas energi home blenderized diabetes melitus berbasis tomat dan susu”, Nutri-Sains: Jurnal Gizi, Pangan Dan Aplikasinya, 5 (2), pp. 125–136.

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